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#synbio

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Darren

#powbio is recruiting a full stack developer to build an intelligent fermentation data and simulation platform. It's a pretty interesting opportunity. The existing code is a mixture of Python, #Fsharp and JavaScript. #GetFediHired. Based in Alameda but open to remote. DM me if you have questions. #precisionfermentation #fermentation #synbio #ai

job-boards.greenhouse.io/powbi

job-boards.greenhouse.ioFull Stack DeveloperRemote or Hybrid
Public
Alexander J. Stein

Scientists found a way to clean up #methylmercury, a dangerous pollutant that builds up in our #environment due to human activities. Fish & flies can be engineered to break down this form of #mercury and remove it from their bodies as a less harmful gas, tackling related #pollution & #foodsafety issues. Species at the top of #foodwebs, incl. humans, can accumulate #mercury at levels that harm neural & reproductive health: lighthouse.mq.edu.au/article/f #health #synbio

The Lighthouse · Scientists engineer fish and flies to clean up toxic mercury
Public
Leibniz-Institut DSMZ

📢 Save the date: Mini symposium on Synthetic Microbiology at the upcoming #VAAM2025
🗓️ Tue, 25 March at 11.15 a.m.
Confirmed invited speaker: Pablo Ivan Nickel (DTU Biosustain)
Hosts: Cecilia Flocco (DSMZ) & Markus Pötter (Evonik Operations GmbH)

programme.conventus.de/vaam-20

programme.conventus.deVAAM 2025 | Session - FG Synthetic microbiology
#syntheticmicrobiology#synbio#lecture
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Tom Howard

We have a new preprint and GitHub page up describing OT-Mation, a script to move experimental arrays generated using statistical Design of Experiments (#DoE) directly in to code to control the OpenTrons OT-2 liquid handling robotics platform. This reduces programming time for the OT-2 and helps prevent inclusion of incorrect experimental combinations in the script.

preprint on biorxiv:
biorxiv.org/content/10.1101/20

GitHub: github.com/tphoward/OT-Mation_

bioRxiv · OT-Mation: an open-source code for parsing CSV files into python scripts for control of OT-2 liquid handling roboticsOT-Mation is an open-source Python script designed to automate the programming of OT-2 liquid handling robots, making combinatorial experiments more accessible to researchers. By parsing user-defined CSV files containing information on labware, reagents, pipettes, and experimental design, OT-Mation generates a bespoke Python script compatible with the OT-2 system. OT-Mation enhances reproducibility, reduces human error, and streamlines workflows, making it a valuable addition to any laboratory utilising OT-2 robotics for liquid handling. While OT-Mation can be used for setting up any type of experiment on the OT-2, its real utility lies in making the connection between multifactorial experimental design software outputs (i.e. Design of Experiments arrays) and liquid-handling robot executable code. As such, OT-Mation helps bridge the gap between code-based flexibility and user-friendly operation, allowing researchers with limited programming skills to design and execute complex experiments efficiently. ### Competing Interest Statement The authors have declared no competing interest.
#SynBio#EngBio#LabAutomation
Public
Nonya Bidniss :CIAverified:

Meet Evo, the DNA-trained AI that creates genomes from scratch; ChatGPT-like model learns on its own to devise new proteins and genetic sequences

"In theory, malicious users could exploit a model like Evo to design a biological weapon, Hie says, so the researchers banished from the AI’s training set sequences from any viruses that attack humans or other eukaryotes, the organisms whose cells boast nuclei."

I'm sure that's 100% effective in a system that "hallucinates" by design. Reminds me of a research project from years ago, this scientist was making a database of genetic sequences that never occur in nature, thereby they would be assumed incompatible with life. #synbio #AI science.org/content/article/me

Picard and Riker facepalm
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